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Hiroyuki Ida Selected Research

Proteasome Inhibitors

1/2015Proteasome Inhibitor Bortezomib Enhances the Activity of Multiple Mutant Forms of Lysosomal α-Glucosidase in Pompe Disease.
11/2011Proteasome inhibitors improve the function of mutant lysosomal α-glucosidase in fibroblasts from Pompe disease patient carrying c.546G>T mutation.

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Hiroyuki Ida Research Topics

Disease

14Gaucher Disease (Gaucher's Disease)
04/2022 - 08/2004
12Mucopolysaccharidosis II (Hunter Syndrome)
05/2021 - 01/2010
10Glycogen Storage Disease Type II (Pompe's Disease)
01/2017 - 05/2010
9Fabry Disease (Fabry's Disease)
06/2022 - 07/2008
7Lysosomal Storage Diseases (Lysosomal Storage Disease)
05/2021 - 05/2014
7Neoplasms (Cancer)
10/2016 - 10/2008
4Mucopolysaccharidoses
04/2021 - 01/2010
4Retinoblastoma (Glioblastoma, Retinal)
10/2016 - 08/2009
3Seizures (Absence Seizure)
04/2022 - 07/2011
3Fibrosis (Cirrhosis)
01/2020 - 01/2013
3Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left)
01/2020 - 12/2015
3Mucopolysaccharidosis I (Hurler Syndrome)
01/2018 - 06/2015
2Progressive Myoclonic Epilepsies (Progressive Myoclonic Epilepsy)
04/2022 - 01/2010
2Drug-Related Side Effects and Adverse Reactions
01/2021 - 10/2014
2Pathologic Constriction (Stenosis)
01/2021 - 11/2017
2Infections
11/2019 - 01/2011
2Hypertrophy
01/2018 - 11/2017
2Body Weight (Weight, Body)
11/2017 - 01/2016
2Febrile Seizures (Febrile Seizure)
01/2017 - 07/2011
2Atrophy
01/2016 - 08/2012
2Metabolic Diseases (Metabolic Disease)
12/2015 - 01/2015
2Asthma (Bronchial Asthma)
07/2011 - 05/2010
2Parkinson Disease (Parkinson's Disease)
09/2010 - 01/2007
2Parkinsonian Disorders (Parkinsonism)
09/2010 - 01/2007
2Sphingolipidoses (Sphingolipidosis)
05/2007 - 08/2004
1Gliosis
06/2022
1Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy)
06/2022
1Myoclonus (Nocturnal Myoclonus)
04/2022
1Prostatic Neoplasms (Prostate Cancer)
03/2022
1Inborn Genetic Diseases (Disease, Hereditary)
09/2021
1Airway Obstruction (Choking)
05/2021
1Congenital Abnormalities (Deformity)
04/2021
1Phenylketonurias (Phenylketonuria)
01/2021
1Supravalvular Aortic Stenosis (Aortic Supravalvular Stenosis)
01/2021
1Maternal Phenylketonuria
01/2021
1Hyperuricemia
01/2021
1Juvenile gout
01/2021
1Bronchiolitis Obliterans Syndrome
01/2020
1Microsatellite Instability
01/2020
1Esophageal Squamous Cell Carcinoma
01/2020
1Aplastic Anemia (Anemia, Hypoplastic)
01/2020
1Glomerulonephritis
11/2019
1Nephritis
11/2019
1Adrenoleukodystrophy (Adrenoleukodystrophy, X-Linked)
01/2019
1Hyperplasia
01/2018
1Aortic Valve Stenosis (Aortic Stenosis)
01/2018

Drug/Important Bio-Agent (IBA)

14GlycosaminoglycansIBA
05/2021 - 09/2012
13EnzymesIBA
06/2022 - 05/2007
10GlucosidasesIBA
09/2021 - 11/2011
10AcidsIBA
09/2021 - 07/2002
6Pharmaceutical PreparationsIBA
04/2022 - 11/2011
6Proteins (Proteins, Gene)FDA Link
11/2019 - 12/2007
4Glucosylceramidase (Glucocerebrosidase)IBA
12/2021 - 01/2007
4alpha-Galactosidase (Beano)IBA
01/2018 - 07/2008
4GlycogenIBA
01/2017 - 05/2010
3Glucose (Dextrose)FDA LinkGeneric
09/2021 - 09/2010
3Iduronic Acid (Iduronate)IBA
12/2020 - 02/2016
3GalactosidasesIBA
07/2019 - 05/2011
3AntibodiesIBA
01/2017 - 10/2012
3Vitamin DFDA LinkGeneric
04/2016 - 05/2010
2eliglustatIBA
09/2021 - 01/2018
2CreatinineIBA
01/2021 - 08/2014
2globotriaosylceramide (globotriosylceramide)IBA
01/2017 - 07/2008
2Telomerase (Telomerase Reverse Transcriptase)IBA
10/2016 - 10/2013
2Hemoglobins (Hemoglobin)IBA
01/2016 - 01/2016
2Proteasome InhibitorsIBA
01/2015 - 11/2011
2Cholecalciferol (Vitamin D3)FDA Link
02/2014 - 05/2010
2human GAA protein (Myozyme)FDA Link
10/2012 - 05/2010
2CytokinesIBA
01/2011 - 12/2007
2Valproic Acid (Depakote)FDA LinkGeneric
10/2010 - 07/2009
2N-octyl-beta-valienamineIBA
05/2007 - 08/2004
2beta-GlucosidaseIBA
05/2007 - 08/2004
1GlycosphingolipidsIBA
06/2022
1perampanelIBA
04/2022
1CeramidesIBA
09/2021
1Glucosylceramides (Glucocerebrosides)IBA
09/2021
1Iduronate SulfataseIBA
05/2021
1Coenzymes (Enzyme Cofactors)IBA
01/2021
1Phenylalanine Hydroxylase (Phenylalanine 4 Monooxygenase)IBA
01/2021
1sapropterin (tetrahydrobiopterin)FDA Link
01/2021
1Phenylalanine (L-Phenylalanine)FDA Link
01/2021
1UromodulinIBA
01/2021
1Therapeutic UsesIBA
12/2020
1GadoliniumIBA
01/2020
1Lysergic Acid Diethylamide (LSD)IBA
01/2020
1NucleotidesIBA
01/2020
1Tacrolimus (Prograf)FDA LinkGeneric
01/2020
1Glyceraldehyde-3-Phosphate Dehydrogenases (GAPD)IBA
11/2019
1plasmin receptorIBA
11/2019
1Mitochondrial Proton-Translocating ATPases (Mitochondrial ATP Synthase)IBA
01/2018
1Heparin (Liquaemin)FDA LinkGeneric
01/2018

Therapy/Procedure

22Enzyme Replacement Therapy
04/2022 - 12/2007
16Therapeutics
04/2022 - 08/2004
5Bone Marrow Transplantation (Transplantation, Bone Marrow)
11/2016 - 05/2011
2Hematopoietic Stem Cell Transplantation
01/2020 - 01/2019
2Radiotherapy
12/2013 - 10/2010
1Activities of Daily Living (ADL)
04/2022
1Castration
03/2022
1Length of Stay
01/2021
1Arterial Switch Operation
01/2021